10 May 2025

The Rejected B Vitamins: Why B4 to B17 Aren’t in Your Multivitamin

Facts The Missing B Vitamins: What Happened to B4, B8, B10–B17?

What Makes a Compound a "Vitamin"?
To be officially classified as a vitamin, a substance must:
Be essential for normal body function
Not be synthesized by the body in sufficient quantities
Cause deficiency diseases when absent from the diet
Be required in small amounts
All the missing "B vitamins" failed to meet one or more of these criteria.

Vitamin B4
Old Names: Choline, Adenine, Carnitine (confused historically)
Choline: Now a conditionally essential nutrient (needed more during pregnancy/liver disease).
Adenine: A DNA/RNA base — not a vitamin, as the body produces it.

Why dropped? These compounds are made in the body or not needed in trace amounts like real vitamins.

Today:

Choline = important, but not a vitamin

Adenine = genetic material component

Carnitine = important for fat metabolism, but made in the body

Vitamin B8
Old Name: Inositol

Role: Supports brain, nerves, insulin sensitivity

Status: Not essential, as body synthesizes inositol from glucose

Why dropped? No disease from inositol deficiency has been identified.

Today:

Used as a supplement (especially for PCOS, anxiety)

Sometimes called a "pseudo-vitamin"

Vitamin B10
Old Name: PABA (Para-Aminobenzoic Acid)

Role: Once thought to be essential for folic acid synthesis in bacteria

Why dropped? Not essential for humans — we don’t make folic acid from PABA

Used in: Sunscreens, hair products, some medicinal uses

Today:

Still sold as a supplement, but not a vitamin

May interfere with sulfa antibiotics

Vitamin B11
Old Name: Pteryl-hepta-glutamic acid, part of folate group

Confusion: In some countries, B11 = folate; in others, it referred to another folate-like compound

Why dropped? Because folate (B9) covered its role

Today:

No longer used as a separate vitamin

Folate = B9, and that’s enough for human needs

Vitamin B13
Old Name: Orotic acid

Role: Involved in DNA/RNA formation and cell growth

Why dropped? Produced by the body, and no known deficiency disease

Still studied for liver support and metabolic disorders

Today:

Used in some supplements, but not considered a vitamin

Vitamin B14
Old Name: Unclear, some say xanthopterin

Role: Once thought to support cell growth

Why dropped? No consistent evidence of benefit or deficiency effect

Today:

Considered obsolete, very little mention in modern science

Vitamin B15
Old Name: Pangamic acid

Used in: USSR and alternative medicine as an “anti-aging” or “oxygenation” compound

Why dropped? No proven benefit, banned in U.S. as a supplement due to safety concerns

Today:

Still sold in some places as “B15,” but not legally recognized as a vitamin

Vitamin B16
Old Name: Dimethylglycine (DMG)

Role: Claimed to boost energy, immunity, endurance

Why dropped? Made by the body and not essential

 Today:

Marketed as an energy or brain supplement, but not a vitamin

Vitamin B17
Old Name: Amygdalin / Laetrile

Found in: Apricot kernels, bitter almonds

Claimed Role: "Anti-cancer vitamin" — but highly controversial and dangerous

Why dropped?

Contains cyanide

No scientific evidence of cancer cure

Banned in many countries

Today:

Sold in alternative circles as “B17,” but NOT a vitamin and potentially toxic

In the 1970s and 1980s:

Laetrile was widely promoted as an alternative cancer cure

Supporters claimed it selectively killed cancer cells

People began eating raw apricot kernels as a natural source

But… 
Apricot kernels contain amygdalin, which the body converts into cyanide — a poison.

Real Cases of Poisoning
Case 1: A 17-year-old girl in the U.S. in the 1980s died of cyanide poisoning after taking Laetrile tablets.

Case 2: In the UK and Australia, multiple cases of acute cyanide toxicity were reported from eating apricot kernels. Some required hospitalization.

Case 3: In 2017, the Australian Medical Association warned against a man who nearly died after taking 17 daily tablets of “natural B17” extract.

Suggested Reading -  

FDA Issues Warning About Toxic Amygdalin Found in Apricot Seeds


Laetrile (amygdalin or vitamin B17)