01 July 2011

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Be Young Forever – Scientist Discover a drug which will reverse aging process Drug has been nicknamed the “forever young” drug

Be Young Forever – Scientist Discover a drug which will
reverse aging process Drug has been nicknamed the “forever young” drug

Scientists have found or discovered a drug and they believe that drug can reverse the effects of premature ageing and could extend human life by more than a decade.

Rapamycin, which has been nicknamed the “forever young” drug, was created from a chemical found in the soil on Easter Island 2,000 miles off the coast of Chile.
One of the remote places on the earth.



Rapamycin is used to suppress the immune system in organ transplants.

What is Progeria?


Progeria, also known as Hutchinson-Gilford Progeria Syndrome (HGPS), is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children.
All children with Progeria die of the same heart disease that affects millions of normal aging adults (arteriosclerosis), but instead of occurring at 60 or 70 years of age, these children may suffer strokes and heart attacks even before age 10.
Remarkably, the intellect of children with Progeria is unaffected, and despite startling physical changes in their young bodies, these extraordinary children are intelligent, courageous, and full of life.

Movie Name – PAA - Big B That is Amitabh Bachchan plays the 13 year old character named Auro who is suffering from Progeria. This disease rapidly accelerates his aging and towards the end of the movie by the time the character hits his teens he dies.

Rapamycin is used in experiments on children suffering from Hutchinson-Gilford Progeria Syndrome (HGPS), a rare genetic condition in which ageing is hyper-accelerated
HGPS suffering patient dies at the age of 12 because of old age.

Rapamycin cleaned the cells of progerin, which swept away the defects and left healthy cells.

What is Progerin?
HGPS starts process whereby a protein called progerin builds up in every cell of the body, causing them to age prematurely.
In 2003, government researchers discovered that the disease is caused by a mutation in the gene for a protein called Lamin A, which helps maintain the normal structure of a cell's nucleus. As a result of the mutation, the cells produce a toxic protein called progerin, which has also been found to accumulate at a much slower rate in normal cells as they age.

In the new study, Cao and her colleagues treated cells from three progeria patients and four healthy individuals with rapamycin in culture.

They observed that the progeria cells showed a reversal in the structural alterations of the nucleus that are associated with the disease and less DNA damage.
The drug also reduced the symptoms of aging in both the progeria and healthy cells. Dr. Dimitri Krainc of the Massachusetts General Hospital Institute for Neurodegenerative Disease, a co-author, demonstrated that the rapamycin activates an intracellular pathway that initiates degradation of proteins not needed by the cells.
The level of progerin in the rapamycin-treated cells declined by half, the team found.

“It is known that during ageing, our cells accumulate by-products of normal cell function,” said Dimitri Krainc, one of the co-authors of the study.

“Our body’s ability to remove this debris declines with ageing and it is thought that even a small activation of this ‘debris removal’ system would extend the health and life-span of our cells and organs.”

NIH Director Dr. Francis Collins, co-author of the study said that "It would be interesting to contemplate if what we learned here can be used to extend our own lifespan."
The experiments may also reveal clues about the normal aging process and how to potentially slow it down

The study is published June 29 in the journal Science Translational Medicine.

The is how the Patient look
Big B in PAA movie –



Reality views by sm –
Friday, July 01, 2011

Keyword – Science News Aging Forever Young Drug Progeria Treatment Health Study

17 comments:

Rekha July 01, 2011  

Forever young but on a messy planet with diminishing resources...a tough choice..

Treat and Trick July 01, 2011  

Didn't know such a drug will soon hit the shelves, thanks for the info...

sm,  July 01, 2011  

Rekha,,
thanks.
yes it will be tough

sm,  July 01, 2011  

Treat and Trick,,
thanks.

Anonymous,  July 01, 2011  

but why would one want to remain young for ever, watching other go away who cant afford ..

I would not want it I am happy and then happy to say BYE too :)


Bikram's

Rama Ananth July 01, 2011  

Even I wouldn't want it.

SM July 01, 2011  

mannbikram,,
thanks.

SM July 01, 2011  

rama,,
thanks.

Destination Infinity July 04, 2011  

Once people start using it, these 'researchers' will come to know about the side effects of this drug after a few years. I personally think this is a hopeless and irresponsible discovery.

Destination Infinity

sm,  July 04, 2011  

Destination Infinity,
thanks.

Anonymous,  August 13, 2011  

that is so wonderful!!! thank you for taking the time to find this

insta August 31, 2011  

Stress, vitamin and mineral deficiencies and excessive food intake speed up the aging process. you have provided good source on knowledge on reverse ageing .

Anonymous,  October 01, 2011  

I believe this would work and would like to get it. Please contact me at: peggyfrz@aol.com

Anonymous,  January 31, 2012  

I have been on this drug for the past 5 1/2 years. I am a transplant recipient. This drug DOES have side effects!! It is an amazing discovery that it extends life - especially giving children with Progeria hope! Side effects include: cystic acne, elevated heart rate, possible capillary leak syndrom, fatigue, amongst MANY others.

David Cruse October 25, 2012  

I have been on this drug for the past 5 1/2 years. I am a transplant recipient. This drug DOES have side effects!! It is an amazing discovery that it extends life - especially giving children with Progeria hope! Side effects include: cystic acne, elevated heart rate, possible capillary leak syndrom, fatigue, amongst MANY others.